Comparing Survival Differences Between Breast-Conserving Therapy and Mastectomy in Patients with Early-Stage Breast Cancer

In 1990 breast-conserving therapy (BCT) was recommended as a preferred treatment for early-stage breast cancer by the NIH consensus statement based on randomized trials demonstrating BCT to have equivalent survival outcomes as mastectomy for early-stage breast cancer patients. BCT became more common while total mastectomy (TM) rates decreased. More recently, patients with early-stage breast cancer are undergoing TM with increasing frequency. In light of increasing TM rates and given significant changes in radiation, surgery and systemic therapies, several groups have examined long-term outcomes for patients undergoing TM vs BCT.

Source: International Journal of Radiation Oncology * Biology * Physics - September 10, 2020 Category: Radiology Authors: Min Yi, Benjamin Smith, Mariana Chavez Mac Gregor, Abigail Caudle, Sarah DeSnyder, Henry Kuerer, Kelly Hunt Source Type: research