Pro-inflammatory lipids precede Type 1 diabetes onset in mouse model and children

(University of Alabama at Birmingham) Type 1 diabetes is an autoimmune disease where immune cells -- led by inflammatory macrophages -- attack and destroy the pancreatic beta cells. It now appears that inflammatory lipid signaling may help provoke this attack. Researchers have identified a proinflammatory lipid profile that precedes development of T1D in a mouse model and in children under age 15 who are at high risk for T1D. This finding may identify candidate lipid therapeutic targets to prevent T1D.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news