NickFect type of cell-penetrating peptides present enhanced efficiency for microRNA-146a delivery into dendritic cells and during skin inflammation.

In conclusion, NF71 efficiently delivers miRNA mimics into KCs as well as DCs, and therefore may have advantage in therapeutic delivery of miRNAs in case of inflammatory skin diseases. PMID: 32896817 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32896817?dopt=Abstract

Source: Biomaterials - August 28, 2020 Category: Materials Science Authors: Carreras-Badosa G, Maslovskaja J, Periyasamy K, Urgard E, Padari K, Vaher H, Tserel L, Gestin M, Kisand K, Arukuusk P, Lou C, Langel Ü, Wengel J, Pooga M, Rebane A Tags: Biomaterials Source Type: research