HOXC10 promotes tumour metastasis by regulating the EMT-related gene Slug in ovarian cancer.

This study provides the first evidence that HOXC10 promotes ovarian cancer metastasis by regulating the transcription of the EMT-related gene Slug. Moreover, we found that HOXC10 is regulated by miR-222-3p. These data highlight the crucial role of HOXC10 in enhancing ovarian cancer metastasis and may provide a therapeutic target for ovarian cancer. PMID: 32897245 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32897245?dopt=Abstract

Source: Aging - September 6, 2020 Category: Biomedical Science Authors: Peng Y, Li Y, Li Y, Wu A, Fan L, Huang W, Fu C, Deng Z, Wang K, Zhang Y, Shu G, Yin G Tags: Aging (Albany NY) Source Type: research