Functional, proteomic, and bioinformatic analyses of Nrf2- and Keap1- null skeletal muscle.

In conclusion, we found that Nrf2 targeted proteins are assigned into two groups: one mediates the tonic effects evoked by a low level of Nrf2 at basal condition; the other is responsible for the inducible effects evoked by a surge of Nrf2 that is dependent on a Keap1 mechanism. This article is protected by copyright. All rights reserved.
PMID: 32893883 [PubMed - as supplied by publisher]

Source: The Journal of Physiology - September 6, 2020 Category: Physiology Authors: Gao L, Kumar V, Vellichirammal NN, Park SY, Rudebush TL, Yu L, Son WM, Pekas EJ, Wafi AM, Hong J, Xiao P, Guda C, Wang HJ, Schultz HD, Zucker IH Tags: J Physiol Source Type: research