Immunohistochemical Analysis of Protective Effects of Maternal Fingolimod on the Placenta and Fetal Lung and Brain in Chorioamnionitis-Induced Preterm Birth Rat Model.

Conclusion: The findings of the present study confirm the neuroprotective effects of antenatally administered fingolimod, which also significantly improved preterm fetal lung injury and placental inflammation in LPS-exposed preterm pregnancies by possible antiapoptotic and anti-inflammatory effects. PMID: 32892670 [PubMed - as supplied by publisher]
Source: Immunopharmacology and Immunotoxicology - Category: Allergy & Immunology Tags: Immunopharmacol Immunotoxicol Source Type: research