Broad host range of SARS-CoV-2 predicted by comparative and structural analysis of ACE2 in vertebrates [Evolution]

The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of COVID-19. The main receptor of SARS-CoV-2, angiotensin I converting enzyme 2 (ACE2), is now undergoing extensive scrutiny to understand the routes of transmission and sensitivity in different species. Here, we utilized a unique dataset of ACE2...

http://www.pnas.org/content/117/36/22311.short?rss=1

Source: Proceedings of the National Academy of Sciences - September 7, 2020 Category: Science Authors: Joana Damas, Graham M. Hughes, Kathleen C. Keough, Corrie A. Painter, Nicole S. Persky, Marco Corbo, Michael Hiller, Klaus-Peter Koepfli, Andreas R. Pfenning, Huabin Zhao, Diane P. Genereux, Ross Swofford, Katherine S. Pollard, Oliver A. Ryder, Martin T. Tags: Coronavirus (COVID-19) Biological Sciences Source Type: research