Observational Study Design Challenges

Recent observational cohort studies have reported a possible association between fluoroquinolone use and aortic aneurysm and aortic dissection (AA/AD). Based on this evidence, the US Food and Drug Administration issued a warning in December 2018 recommending avoiding fluoroquinolone use in patients with AA/AD or who are at risk for these conditions.

https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2770358

Source: JAMA Internal Medicine - September 8, 2020 Category: Internal Medicine Source Type: research

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