Clinical characteristics and long ‐term outcomes of peripartum takotsubo cardiomyopathy and peripartum cardiomyopathy

ConclusionsOne ‐third of pregnancy‐associated cardiomyopathy patients had peripartum TCM. With contemporary supportive care, both PPCM and peripartum TCM patients had a low mortality rate and excellent long‐term outcomes.
Source: ESC Heart Failure - Category: Cardiology Authors: Tags: Original Research Article Source Type: research

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Publication date: Available online 27 September 2019Source: Journal of Cardiology CasesAuthor(s): Chihiro Takuwa-Shiomi, Masataka Ogiso, Toshiaki Isogai, Ken Kato, Hiroyuki Tanaka, Takahiro Kiriu, Ai Masukawa, Hiroshi Niinami, Nobuhisa HagiwaraAbstractPeripartum cardiomyopathy (PPCM) is a rare disorder in which left ventricular (LV) systolic dysfunction and symptoms of heart failure (HF) occur in the peripartum period. The time to potential recovery from severe remodeling of ventricular function is difficult to predict. Although lack of late gadolinium enhancement (LGE) in cardiovascular magnetic resonance (CMR) is reporte...
Source: Journal of Cardiology Cases - Category: Cardiology Source Type: research
Peripartum cardiomyopathy (PPCM) is a rare, but serious and potentially life-threatening condition. The nursing hormone Prolactin has been hypothesized as potential pathogenic factor of PPCM. Positive family history could be a reason for genetically caused peripartum heart failure that has possibly been demasked by the physiological pregnancy stress in a subset of patients. From animal models mutations in STAT3 may be involved in these genetic forms of PPCM.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: 969 Source Type: research
AbstractPurpose of reviewThis review summarizes the pathophysiology, diagnosis, and treatment of peripartum cardiomyopathy (PPCM), with a focus on recent discoveries of clinical relevance.Recent findingsAn increase in oxidative stress and anti-angiogenic activity play key roles in the pathophysiology of peripartum cardiomyopathy. Therapies that target this dysregulation may have a future role in treatment. Suppression of prolactin release using bromocriptine, a dopamine-receptor antagonist, has been associated with more favorable outcomes in small studies but more research is needed. Similarly, VEGF agonists may prove to b...
Source: Current Treatment Options in Cardiovascular Medicine - Category: Cardiology Source Type: research
This article is part of the Mini Review Series from the Varenna 2017 meeting of the Working Group of Myocardial Function of the European Society of Cardiology.
Source: Cardiovascular Research - Category: Cardiology Source Type: research
We describe contraception for two groups of women: (1) women with heart failure and (2) women with cardiac transplantation. RECENT FINDINGS: Medical Eligibility Criteria for contraceptive agents address women with peripartum cardiomyopathy and women with valvular heart disease (Curtis et al. MMWR Recomm Rep 65:1-103, 2016). Recommendations for women with other forms of heart failure are extrapolated from these populations. Recommendations for women with cardiac transplantation have shifted since the 1980s: use of long-acting reversible contraception has increased, and there is a better understanding of the interaction...
Source: MMWR Recomm Rep - Category: Epidemiology Authors: Tags: Curr Heart Fail Rep Source Type: research
We describe contraception for two groups of women: (1) women with heart failure and (2) women with cardiac transplantation.Recent FindingsMedical Eligibility Criteria for contraceptive agents address women with peripartum cardiomyopathy and women with valvular heart disease (Curtis et al. MMWR Recomm Rep 65:1 –103,2016). Recommendations for women with other forms of heart failure are extrapolated from these populations. Recommendations for women with cardiac transplantation have shifted since the 1980s: use of long-acting reversible contraception has increased, and there is a better understanding of the interactions ...
Source: Current Heart Failure Reports - Category: Cardiology Source Type: research
Conclusions: Long-term outcomes following HT for PPCM are favorable. Heart transplantation is a valuable option for PPCM patients who did not recover significantly under medical treatment.Resumo Fundamento: A cardiomiopatia periparto é uma doença idiopática definida pela ocorrência de insuficiência cardíaca aguda durante a gravidez tardia ou pós-parto na ausência de qualquer outra causa definível. Seu curso clínico é variável e casos graves podem exigir transplante. cardíaco. Objetivo: Pesquisar os resultados a lon go prazo após ...
Source: Arquivos Brasileiros de Cardiologia - Category: Cardiology Source Type: research
ConclusionThe first validated, population‐based European estimate of PPCM incidence is 1 in 10 149 deliveries, which places Denmark between American and Japanese estimates. Clinical outcome in the cohort was similar to those reported in recent cohorts. Women with concomitant hypertensive disorder of pregnancy had a milder course of PPCM. Baseline LVEF predicted LVEF 10–14 months after diagnosis and cabergoline predicted complete recovery.
Source: European Journal of Heart Failure - Category: Cardiology Authors: Tags: ORIGINAL ARTICLE Source Type: research
Abstract: Peripartum cardiomyopathy (PPCM), often classified as a form of dilated cardiomyopathy (DCM), is the myocardial dysfunction that occurs in late pregnancy and through the first few postpartum months. The aim of this study is to investigate the differences in the clinical outcomes of PPCM and DCM. Electronic medical records from 1997 to 2011 were retrieved from the Taiwan National Health Insurance Research Database. Patients with PPCM were compared with age- and clinical characteristics-matched patients with DCM. Primary outcomes were 1- and 3-year heart failure (HF) readmission, cardiac death, all-cause mortalit...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
ConclusionsFactors other than focal myocardial damage detectable by LGE explain the initial transient depressions in baseline left ventricular ejection fraction, yet focal myocardial damage may contribute to persistent myocardial dysfunction and hinder recovery in a small minority. Most women exhibit favorable changes in ventricular function over 6 months.Clinical Trial RegistrationURL: http://www.clinicaltrials.gov. Unique identifier: NCT01085955.
Source: JAHA:Journal of the American Heart Association - Category: Cardiology Authors: Tags: Cardiomyopathy, Heart Failure Original Research Source Type: research
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