Correlation between CXCR4, CXCR5 and CCR7 expression and survival outcomes in patients with clinical T1N0M0 non ‐small cell lung cancer

ConclusionsExpression levels of CXCR4, CXCR5 and CCR7 were significantly higher in tumor tissues, and expression of CXCR5 and CCR7 were independent prognostic factors for survival. Moreover, all three chemokines were correlated to the survival outcomes of patients with clinical T1N0M0 NSCLC, providing potential prognosticators and therapy targets for lung cancer treatment.

Source: Thoracic Cancer - September 7, 2020 Category: Cancer & Oncology Authors: Zhao Yue, Ding Ningning, Yang Lin, Ying Jianming, Zhang Hongtu, Yuan Ligong, Li Feng, Wang Shuaibo, Mao Yousheng Tags: ORIGINAL ARTICLE Source Type: research