The Curious Phenomenon of Early Cardiac Allograft Rejection with Hepatitis C Infected Donor Heart Transplants

In recent years, emerging data has demonstrated that organs from Hepatitis C Virus (HCV)-infected donors can be transplanted into uninfected recipients with excellent outcomes. Critical to this success is the use of pre-emptive or prophylactic direct-acting antiviral (DAA) therapy, with the intent to minimize any viral transmission and block viral replication. The optimal timing to employ such therapy, whether at the time of transplant or following the detection of viremia, remains a matter of ongoing debate.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: Editorial Source Type: research