Management for a patient of moyamoya disease presenting with ischemic stroke in the first trimester of pregnancy

We report an extremely rare case of a 27-year-old woman presenting with ischemic stroke as an initial manifestation of moyamoya disease in the first trimester of pregnancy. We conducted an artificial abortion when her neurological symptoms rapidly became refractory to optimal antithrombotic treatments. The progression of neurologic deficits stopped immediately after abortion, resulting in recovery to independence, with slight motor aphasia and right hemiparesis due to improved cerebral flow. We highlight rapid artificial abortion combined with antithrombotic treatment for patients of moyamoya disease with pregnancy-associated ischemic stroke as an appropriate treatment to correct hemodynamic instability and suppress the progression of neurological symptoms.

Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2020 Category: Neurology Authors: Masashi Watanabe, Kanehisa Kohno, Tomoki Shinohara, Toshimoto Seno, Satoshi Fujiwara, Shinji Onoue, Shinya Fukumoto, Haruhisa Ichikawa, Shinji Iwata, Kensho Okamoto, Shiro Ohue Tags: Case Report Source Type: research