Genetic spectrum and predictors of mutations in four known genes in Asian Indian patients with growth hormone deficiency and orthotopic posterior pituitary: an emphasis on regional genetic diversity

ConclusionAt variance with world literature, we found reverse predominance ofGHRHR overGH1 mutations,POU1F1 overPROP1 mutations and predominance ofGHRHR p.Glu72* mutations thus re-affirming the regional diversity in GHD genetics. We report positive and negative predictors of mutations in GHD.
Source: Pituitary - Category: Endocrinology Source Type: research