Novel basophil activation test in diagnosis of povidone anaphylaxis

Medications generally contain two components: the active ingredient – intended to produce the desired therapeutic effect, and excipients – inactive ingredients added for purposes such as improving absorption and product stability. Although considered inert, excipients may represent occult allergens capable of causing allergic reactions. To date, thirty-eight exc ipients have been described to cause symptoms, with an increasing number of reports documenting type 1 hypersensitivity reactions1.

Source: Annals of Allergy, Asthma and Immunology - September 6, 2020 Category: Allergy & Immunology Authors: Kavitha Garuna Murthee, Nirupama Varese, Mark Hew, Robyn E. O ’Hehir, Celia Zubrinich Tags: Letters Source Type: research