The Utility of Serum Creatinine Kinase in Emergency Department Patients with Possible Substance-use Related Conditions

Introduction: Our goal was to assess the diagnostic utility and temporal kinetics of serum creatine kinase (CK) measurement as a predictor of acute kidney injury (AKI) in emergency department (ED) patients who present with possible substance-use related conditions.Methods: This was a retrospective chart review of ED patients with a urine drug screen (UDS) ordered and resulted between 2009 –2013. Data was extracted electronically from EPIC Systems electronic health records, populated into a Microsoft Excel file, and includes demographics, chief complaint, vital signs, neuro-psychiatric physical examination findings, laboratory findings, psychiatric consult order time, ED medications given, orders, disposition and its time, and diagnosis.Results:Of 74,970 patients with an ED UDS, 22,101 (29%) had at least one CK measured. After inclusion and exclusion criteria, 2858 (13%) remained. Mean (standard deviation [SD])...
Source: Western Journal of Emergency Medicine - Category: Emergency Medicine Source Type: research