Two new homoisoflavones from Portulaca oleracea L. and their activities.

Two new homoisoflavones from Portulaca oleracea L. and their activities.
Nat Prod Res. 2020 Sep 03;:1-9
Authors: Duan Y, Ying Z, Zhang M, Ying X, Yang G
Abstract
Two new compounds, identified as 3-(2-hydroxybenzyl)-6,8-dimethoxy-4H-chromen-4-one (1), named oleracone J and 3-(2-hydroxybenzyl)-6,8-dimethoxychroman-4-one (2), named oleracone K, were isolated from Portulaca oleracea L., and the structures of them were determined by spectroscopy, including one-dimensional and two-dimensional nuclear magnetic resonance, high-resolution electrospray ionisation time-of-flight mass spectrometry. The two compounds have scavenging activities in 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical quenching assay, with IC50 values of 18.34, 23.92 μM, and anticholinesterase activities with IC50 values of 59.08, 67.89 μM, respectively.
PMID: 32878500 [PubMed - as supplied by publisher]

Source: Natural Product Research - September 2, 2020 Category: Biochemistry Authors: Duan Y, Ying Z, Zhang M, Ying X, Yang G Tags: Nat Prod Res Source Type: research