Fluid Bolus in Hypotensive Septic Shock: Need to Encourage Critical Care Interventions Outside the Formal PICU
No abstract available
Publication date: October 2020Source: Archives of Cardiovascular Diseases Supplements, Volume 12, Issues 2–4Author(s): A. Bangy-Letheule, F. Souab, S. Bourgoin, S. Michelland, V. Cunin, M. Seve, V. Aillerie, J. Dhot, J. Montnach, A. Persello, B. Rozec, B. Lauzier, M. De Waard
Publication date: Available online 24 September 2020Source: Acta Pharmaceutica Sinica BAuthor(s): Zhilei Wang, Guang Xu, Yuan Gao, Xiaoyan Zhan, Nan Qin, Shubin Fu, Ruisheng Li, Ming Niu, Jiabo Wang, Youping Liu, Xiaohe Xiao, Zhaofang Bai
Authors: Kurihara Y, Maruhashi T, Wada T, Osada M, Oi M, Yamaoka K, Asari Y Abstract Severe coronavirus disease (COVID-19) can induce serious complications, including acute respiratory distress syndrome, septic shock, and acute kidney injury. However, few reports have associated COVID-19 with pancreatitis. We herein report the case of a 55-year-old patient who developed acute pancreatitis associated with severe COVID-19 pneumonia and was successfully treated with veno-venous extracorporeal membrane oxygenation (ECMO). Elevated pancreatic enzymes levels and computed tomography findings led to the diagnosis of acute ...
An index combining respiratory rate and oxygenation (ROX) has been introduced, and the ROX index is defined as the ratio of oxygen saturation by pulse oximetry/fraction of inspired oxygen to respiratory rate. In sepsis, hypoxemia and tachypnea are commonly observed. We performed this study to investigate the association between the ROX index and 28-day mortality in patients with sepsis or septic shock.
Authors: Philips CA, Ahamed R, Rajesh S, George T, Mohanan M, Augustine P Abstract Sepsis and septic shock are catastrophic disease entities that portend high mortality in patients with cirrhosis. In cirrhosis, hemodynamic perturbations, immune dysregulation, and persistent systemic inflammation with altered gut microbiota in the background of portal hypertension enhance the risk of infections and resistance to antimicrobials. Patients with cirrhosis develop recurrent life-threatening infections that progress to multiple organ failure. The definition, pathophysiology, and treatment options for sepsis have been ever...
Sepsis is not a monolithic disease, but a loose collection of symptoms with diverse outcomes. Thus, stratification and subtyping of sepsis patients is of great importance. We examine the temporal evolution of patient state using our previously-published method for computing risk of transition from sepsis into septic shock. Risk trajectories diverge into four clusters following early prediction of septic shock, stratifying by outcome: the highest-risk and lowest-risk groups have a 76.5% and 10.4% prevalence of septic shock, and 43% and 18% mortality, respectively. These clusters differ also in treatments received and median...
ConclusionIn this nested case –control study, we demonstrated a significant association between IAH and high-dose glucocorticoid with significant duration–response effects. Serum sodium concentrations should be monitored carefully in critically ill patients administered prolonged high-dose glucocorticoid.
Publication date: Available online 18 September 2020Source: Journal of Critical CareAuthor(s): Xiaoming Li, Chao Liu, Zhi Mao, Shuang Qi, Renjie Song, Feihu Zhou
Publication date: Available online 17 September 2020Source: Journal of Critical CareAuthor(s): Brittany R. Kiracofe, Bruce A. Doepker, Heidi M. Riha, Rachel Wilkinson, Elizabeth Rozycki, Eric Adkins, Amy Lehman, Megan A. Van Berkel