T cell receptor repertoires of ex vivo – expanded tumor-infiltrating lymphocytes from breast cancer patients

In this study, we identified a heterogeneous pattern of expanded T cell clones and stable usage of V/J segments in ex vivo–expanded TILs from breast cancer patients. Further large-scale studies are requisite to elucidate the clinical significance of TCR repertoires .

http://link.springer.com/10.1007/s12026-020-09150-8

Source: Immunologic Research - August 27, 2020 Category: Allergy & Immunology Source Type: research