A fatal case of coronavirus disease 2019 in a patient with common variable immunodeficiency

Common variable immunodeficiency (CVID) is a heterogeneous group of primary immunodeficiency syndromes characterized by hypogammaglobulinemia and impaired vaccine responses. Although immunodeficiency is described as a risk factor for coronavirus disease 2019 (COVID-19), limited data are available regarding CVID. Of note, 3 recent reports describe mostly positive outcomes in patients with CVID who were diagnosed as having COVID-19,1-3 with only 1 fatality.3 All these patients had adequate immunoglobulin G (IgG) levels at the time of COVID-19 diagnosis.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Letters Source Type: research