Multifactorial intervention has a significant effect on diabetic kidney disease in patients with type 2 diabetes.

To evaluate the effect of multifactorial intervention on the onset and progression of diabetic kidney disease in the patients with type 2 diabetes, we analyzed the effects of intensified multifactorial intervention (intensive therapy treatment targets; HbA1c under 6.2%, blood pressure under 120/75 mmHg, low-density lipoprotein cholesterol under 80 mg/dL) comparing with step-wise intensification of medications and life-style modifications of guideline-based standard care (conventional therapy treatment targets: HbA1c under 6.9%, blood pressure under 130/80 mmHg, low-density lipoprotein cholesterol under 120 mg/dL) on diabetic kidney disease.

Source: Kidney International - September 2, 2020 Category: Urology & Nephrology Authors: Kohjiro Ueki, Takayoshi Sasako, Yukiko Okazaki, Kana Miyake, Masaomi Nangaku, Yasuo Ohashi, Mitsuhiko Noda, Takashi Kadowaki, J-DOIT3 Study Group Tags: clinical trial Source Type: research