[Primary liver tumors : Hepatocellular versus intrahepatic cholangiocellular carcinoma.]

[Primary liver tumors : Hepatocellular versus intrahepatic cholangiocellular carcinoma.]
Radiologe. 2015 Jan 11;
Authors: Wengert GJ, Bickel H, Breitenseher J, Ba-Ssalamah A
Abstract
CLINICAL ISSUE: Hepatocellular carcinoma (HCC) and intrahepatic cholangiocellular carcinoma (ICC) are the most commonly occurring and important primary liver tumors. Originating from one pluripotent liver stem cell both tumor entities can occur in a cirrhotic liver and also in patients without cirrhosis. Several risk factors have been identified as causative for both carcinomas; therefore, tumor screening is advantageous, especially for high-risk patients who could be diagnosed in an early stage to allow curative treatment. Surgical resection, interventional procedures and transplantation are available as curative treatment options when diagnosed in time.
STANDARD RADIOLOGICAL METHODS: Common characteristic features and morphology in cross-sectional imaging by ultrasound (US), multidetector computed tomography (CT) and magnetic resonance imaging (MRI) as well as screening aspects are presented and discussed.
METHODICAL INNOVATIONS: Recent findings show a better understanding of the carcinogenesis model of both liver tumors originating from one pluripotent liver stem cell. Further developments of modern cross-sectional imaging modalities, especially MRI in combination with diffusion-weighted imaging and intravenous administration of hepato...

Source: Der Radiologe - January 11, 2015 Category: Radiology Authors: Wengert GJ, Bickel H, Breitenseher J, Ba-Ssalamah A Tags: Radiologe Source Type: research