Black Lives and Black Donors Matter Post-Hematopoietic Stem Cell Transplantation

Solomon et al [1], reporting for the Center for International Blood and Marrow Transplantation Research (CIBMTR), compare outcomes in African American adults (age 18 to 70 years) with a hematologic malignancy (acute myelogenous leukemia, acute lymphoblastic leukemia, myelodysplastic syndrome, or non-Hodgkin lymphoma) following T cell-replete haploidentical stem cell transplantation (haploSCT) with post- haploSCT cyclophosphamide versus unrelated umbilical cord blood transplantation (UCBT). The UCBT group included both single (>2.5  × 107total nucleated cells [TNCs]/kg) and double (>1.5  × 107 TNCs/kg) units with a 1 or 2 HLA mismatch (ie, low-resolution typing at HLA-A and -B and allele-level typing at -DRB1).
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Tags: Commentary Source Type: research