The μ-opioid receptor gene polymorphism 118A > G weakens the pharmacological action of buprenorphine.

CONCLUSION: Levels of pharmacological actions of a μ-opioid receptor partial agonist vary in accordance with a polymorphism in the OPRM1 gene (A118G). PMID: 32870152 [PubMed - as supplied by publisher]
Source: International Journal of Clinical Pharmacology and Therapeutics - Category: Drugs & Pharmacology Tags: Int J Clin Pharmacol Ther Source Type: research