Potential monoamine oxidase A inhibitor suppressing paclitaxel ‐resistant non‐small cell lung cancer metastasis and growth

ConclusionsThese findings indicated G11 showed a moderate inhibitory effect on paclitaxel ‐resistant NSCLC metastasis and growth, and support further investigation on MAOA potentially as a promising therapeutic target for paclitaxel‐resistant NSCLC treatment.Key pointsSignificant findings of the study Inhibition of MAOA might contribute to the suppression of metastasis and growth in PTX ‐resistant NSCLC cells.What this study adds This study explored the potential function of MAOA in drug ‐resistant NSCLC and might consider MAOA as a promising target for the treatment of drug‐resistant NSCLC.
Source: Thoracic Cancer - Category: Cancer & Oncology Authors: Tags: ORIGINAL ARTICLE Source Type: research