Vagally Mediated Heart Rate Variability Is Associated With Executive Function Changes in Patients With Treatment ‐Resistant Depression Following Magnetic Seizure Therapy

ConclusionsSince this is an open ‐label trial, the influence of the placebo effect cannot be excluded. However, our results suggest that baseline RMSSD may be a state‐biomarker of depression and executive function impairment. Additionally, while baseline vagally mediated resting cardiac activity did not predict the outcome of d epression, it may mediate executive function improvements following MST.

Source: Neuromodulation: Technology at the Neural Interface - August 31, 2020 Category: Biotechnology Authors: Yoshihiro Noda, Yuliya Knyahnytska, Reza Zomorrodi, Jonathan Downar, Tarek K. Rajji, Zafiris J. Daskalakis, Daniel M. Blumberger Tags: Clinical Research Source Type: research