Physiological profile regulation during weight gain and loss by ovariectomized females: importance of SIRT1 and SIRT4.

CONCLUSION: Weight cycle suggested that mitochondrial and nuclear sirtuins were active in cellular signaling for the control lipids metabolism, oxidative phosphorylation and redox status. Weight cycling was able to restore the characteristics of the health of lean animals. PMID: 32865007 [PubMed - as supplied by publisher]
Source: American Journal of Physiology. Endocrinology and Metabolism - Category: Physiology Authors: Tags: Am J Physiol Endocrinol Metab Source Type: research