Paradoxical Low-Flow Low-Gradient Aortic Stenosis: Effect of Low Transvalvular Flow Conditions on Indexed Stroke Volume after Transcatheter Aortic Valve Replacement

Paradoxical low-flow low-gradient aortic stenosis (P-LFLG AS) is a high-risk yet incompletely understood subset of severe AS,1 for which studies have not uniformly noted improved outcomes after aortic valve replacement.2,3 Several vascular, valvular, and myocardial conditions contribute to low transvalvular flow (LF) across stenosed aortic valves.4 The cumulative burden of LF conditions may affect hemodynamic improvement after transcatheter aortic valve replacement (TAVR) and explain the aforementioned varying survival benefits.

Source: Journal of the American Society of Echocardiography - August 31, 2020 Category: Cardiology Authors: Nisha Hosadurg, Benjamin Koethe, Dou Huang, Andrew R. Weintraub, Ayan R. Patel, Benjamin S. Wessler Tags: Brief Research Communication Source Type: research