Immune Response Distinguishes Celiac Disease From Gluten Sensitivity Immune Response Distinguishes Celiac Disease From Gluten Sensitivity

The IgG antibody response to gluten is different in people with celiac disease and non-celiac gluten sensitivity, respectively, researchers report.Reuters Health Information
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Gastroenterology News Source Type: news

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Allergy Asthma Immunol Res. 2021 Sep;13(5):697-718. doi: 10.4168/aair.2021.13.5.697.ABSTRACTOur prior work and the work of others have demonstrated that asthma increases the risk of a broad range of both respiratory (e.g., pneumonia and pertussis) and non-respiratory (e.g., zoster and appendicitis) infectious diseases as well as inflammatory diseases (e.g., celiac disease and myocardial infarction [MI]), suggesting the systemic disease nature of asthma and its impact beyond the airways. We call these conditions asthma-associated infectious and inflammatory multimorbidities (AIMs). At present, little is known about why some...
Source: Allergy, Asthma and Immunology Research - Category: Allergy & Immunology Authors: Source Type: research
CONCLUSION: the validated recipes are of clinical and research interest, as they allow to confirm a peanut allergy and detect a wide range of tolerated threshold doses, which makes it possible to provide specific indications for each patient.PMID:34233225 | DOI:10.1016/j.anai.2021.06.024
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Source Type: research
J Proteomics. 2021 Jul 2:104318. doi: 10.1016/j.jprot.2021.104318. Online ahead of print.ABSTRACTBACKGROUND/OBJECTIVES: Cereal products like flour and bread are known to trigger diseases such as wheat allergy, celiac disease and non-celiac wheat sensitivity (NCWS). Some of these diseases are caused by allergenic proteins, the expression of which might vary depending on the grain type and manufacturing processes. Therefore, we examined the protein composition and abundance of potentially allergenic proteins in flours from bread wheat, spelt and rye, and corresponding breads.MATERIALS AND METHODS: Using Nano-LC-ESI-MS/MS and...
Source: Journal of Proteomics - Category: Biochemistry Authors: Source Type: research
Conclusions: Surgical total thyroidectomy and anti-TPO Ab-related autoimmunity appear to play a beneficial role and definitive role in the remission of AAI in HT.
Source: Nigerian Journal of Clinical Practice - Category: Rural Health Authors: Source Type: research
In recent years, the prevalence of large spectrum of gluten-related disorders (GRDs) has increased. Gluten is one of the most widely distributed components of food in both industrialized and developing countries. The main structural protein complex of wheat and its proteins are classified into albumins, salt-soluble globulins, and insoluble prolamins (gliadins and glutenins). Gluten is also included in other cereals, including rye and barley. GRDs can be classified, based on their pathogenic mechanism, into (i) Autoimmune disorders, (ii) Allergic disorders, (iii) No autoimmune, not allergic disorders. Coeliac disease (CD) ...
Source: Current Nutrition and Food Science - Category: Nutrition Source Type: research
Medicina (Kaunas). 2021 May 24;57(6):526. doi: 10.3390/medicina57060526.ABSTRACTNon-celiac gluten sensitivity (NCGS) is a clinical entity characterized by the absence of celiac disease and wheat allergy in patients that trigger reproducible symptomatic responses to gluten-containing foods consumption. Due to the lack of sensitive and reproducible biomarkers for NCGS diagnosis, placebo-controlled gluten challenges must be carried out for its diagnosis. The gluten challenges can be either double- or single-blind, for research or clinical practice purposes, respectively. For improving our understanding about the magnitude and...
Source: Medicina (Kaunas) - Category: Universities & Medical Training Authors: Source Type: research
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