Treatment-Specific Associations Between Brain Activation and Symptom Reduction in OCD Following CBT: A Randomized fMRI Trial.

CONCLUSIONS: The study findings demonstrate that associations between brain activation and treatment response were treatment specific to CBT relative to a control psychotherapy and that these associations were stable from adolescence to mature adulthood. Such treatment-specific associations are important for the development of biomarkers to personalize treatment in OCD.
PMID: 32854533 [PubMed - as supplied by publisher]

Source: The American Journal of Psychiatry - August 27, 2020 Category: Psychiatry Authors: Norman LJ, Mannella KA, Yang H, Angstadt M, Abelson JL, Himle JA, Fitzgerald KD, Taylor SF Tags: Am J Psychiatry Source Type: research