Colon and rectal cancer cases are going up among people younger than 50, researchers say

Colon and rectal cancer cases are on the rise in young adults -- with half of all new diagnoses in people age 66 and younger. And cases among those under 50 have been increasing since the 1990s.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news

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This study aims to analyze the presentation pattern and outcomes of sporadic rectal cancer in adolescents and young adults. DESIGN: This is a retrospective study. SETTING: This study was conducted at 3 European tertiary centers. PATIENTS: Data on adolescents and young adults operated on for sporadic rectal cancer (January 2008 through October 2019) were analyzed. To compare outcomes, adolescents and young adults were matched to a group of patients aged ≥40 operated on during the same period. MAIN OUTCOME MEASURES: The primary outcomes measured were clinical presentation and long-term outcomes...
Source: Diseases of the Colon and Rectum - Category: Gastroenterology Tags: Original Contributions: Colorectal Cancer Source Type: research
CONCLUSION: In managing Signet cell carcinoma of the colorectal, physician have to know that it has a poor prognosis in patients of any age. However, in young teenagers delayed diagnosis and treatment option are narrowed to palliative management. Genetic profiling of family members and similar environment population may be a key to early detection.PMID:34007446 | PMC:PMC8111589 | DOI:10.1016/j.amsu.2021.102353
Source: Annals of Medicine - Category: Internal Medicine Authors: Source Type: research
Colon and rectal cancer cases are on the rise in young adults -- with half of all new diagnoses in people age 66 and younger. And cases among those under 50 have been increasing since the 1990s.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news
ConclusionThis is, to our knowledge, the first scoping review presenting the range of available evidence on CRC in AYAs. Although the rise in incidence is recognised by specialist bodies, recommendations are limited by the sparsity of available data. We seek to highlight the need for further research, define the role of earlier screening and raise awareness to promote thorough assessment of young patients.
Source: International Journal of Colorectal Disease - Category: Gastroenterology Source Type: research
ConclusionThe increase of early-onset CRC incidence suggests more prevention initiatives are urgently warranted for young adults in the near future. Targeted and effective prevention measures are still needed among elderly populations.
Source: International Journal of Colorectal Disease - Category: Gastroenterology Source Type: research
Colon and rectal cancer cases are on the rise in young adults, according to a new report from the American Cancer Society.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news
Conclusions: We found age-related disparities in CRC incidence and IBM between individuals under age 50 and age 50 years and older. Increasing incidence rates of rectal cancer substantially accounts for this disparity among individuals under age 50. The escalating trends of early-onset CRC warrant investigation into the factors leading to the population-level trends. PMID: 31827515 [PubMed]
Source: Journal of Cancer Epidemiology - Category: Epidemiology Tags: J Cancer Epidemiol Source Type: research
In conclusion, colorectal cancer in young adults occurs without obvious risk factors in Burkina Faso. Mortality remains high because of the limited therapeutic arsenal. PMID: 31615647 [PubMed - as supplied by publisher]
Source: Bulletin du Cancer - Category: Cancer & Oncology Authors: Tags: Bull Cancer Source Type: research
Publication date: December 2019Source: Cancer Epidemiology, Volume 63Author(s): Olatunji B. Alese, Renjian Jiang, Katerina M. Zakka, Christina Wu, Walid Shaib, Mehmet Akce, Madhusmita Behera, Bassel F. El-RayesAbstractBackgroundThe incidence of colorectal cancer (CRC) in young adults is increasing. Minority populations with CRC are known to have worse survival outcomes. The aim of this study is to evaluate adults under age 50 years with CRC by race and ethnicity.MethodsData were obtained from all US hospitals that contributed to the National Cancer Database (NCDB) between 2004 and 2013. Univariate and multivariable testing...
Source: Cancer Epidemiology - Category: Cancer & Oncology Source Type: research
In contrast to the decreasing incidence of colorectal cancer (CRC) in older populations, the incidence has nearly doubled in younger adults since the early 1990s. Approximately 1 in 10 new diagnoses of CRC are now made in individuals 50 years or younger. Patients ’ risk of CRC has been calculated largely by age and family history, yet 3 of 4 patients with early-onset CRC have no family history of the disease. Rapidly increasing incidence rates in younger persons could result from generational differences in diet, environmental exposures, and lifestyle fact ors.
Source: Gastroenterology - Category: Gastroenterology Authors: Source Type: research
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