CpG-postconditioning after reperfused myocardial infarction is associated with modulated inflammation, less apoptosis and better left ventricular function.

CONCLUSION: Our study suggests a cardioprotective mechanism of CpG-postconditioning, involving TLR-driven modulation of inflammation. This is followed by attenuated remodeling and preserved LV-function. PMID: 32857588 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32857588?dopt=Abstract

Source: American Journal of Physiology. Heart and Circulatory Physiology - August 27, 2020 Category: Physiology Authors: Duerr GD, Wu S, Schneider ML, Marggraf V, Weisheit CK, Velten M, Verfuerth L, Frede S, Boehm O, Treede H, Dewald O, Baumgarten G, Kim SC Tags: Am J Physiol Heart Circ Physiol Source Type: research