ERN1 knockdown modifies the effect of glucose deprivation on homeobox gene expressions in U87 glioma cells.

CONCLUSIONS: The results of this investigation demonstrate that ERN1 knockdown significantly modifies the sensitivity of most studied homeobox gene expressions to glucose deprivation condition and that these changes are a result of complex interaction of variable endoplasmic reticulum stress related and unrelated regulatory factors and contributed to glioma cell growth and possibly to their chemoresistance. PMID: 32857719 [PubMed - as supplied by publisher]
Source: Endocrine Regulations - Category: Endocrinology Tags: Endocr Regul Source Type: research