Effect of menopausal hormone therapy on proteins associated with senescence and inflammation

ConclusionsCirculating levels of some markers of cell senescence were lower in menopausal women treated with oCEE and tE2 compared to placebo. Differences in the magnitude of effect of the two active treatments may reflect the differences in circulating levels of estrogen metabolites due to formulation and mode of delivery. These data generate new hypotheses with regard to the effects of menopause on the biology of aging.

Source: Physiological Reports - August 27, 2020 Category: Physiology Authors: Laura Faubion, Thomas A. White, Brett J. Peterson, Jennifer R. Geske, Nathan K. LeBrasseur, Marissa J. Schafer, Michelle M. Mielke, Virginia M. Miller Tags: ORIGINAL RESEARCH Source Type: research