Proton pump inhibitors for chronic obstructive pulmonary disease.

CONCLUSIONS: Evidence identified by this review is insufficient to determine whether treatment with PPIs is a potential option for COPD. The sample size of the included trial is small, and the evidence is low to very low-certainty. The efficacy and safety profile of PPIs for people with COPD remains uncertain. Future large-scale, high-quality studies are warranted, which investigate major clinical outcomes such as COPD exacerbation rate, serious adverse events and quality of life.
PMID: 32844430 [PubMed - in process]

Source: Cochrane Database of Systematic Reviews - August 24, 2020 Category: General Medicine Authors: Kikuchi S, Imai H, Tani Y, Tajiri T, Watanabe N Tags: Cochrane Database Syst Rev Source Type: research