Interventions for American cutaneous and mucocutaneous leishmaniasis.

CONCLUSIONS: Evidence certainty was mostly moderate or low, due to methodological shortcomings, which precluded conclusive results. Overall, both IMMA and oral miltefosine probably result in an increase in cure rates, and nausea and vomiting are probably more common with miltefosine than with IMMA. Future trials should investigate interventions for mucosal leishmaniasis and evaluate recurrence rates of cutaneous leishmaniasis and its progression to mucosal disease.
PMID: 32853410 [PubMed - in process]

Source: Cochrane Database of Systematic Reviews - August 26, 2020 Category: General Medicine Authors: Pinart M, Rueda JR, Romero GA, Pinzón-Flórez CE, Osorio-Arango K, Silveira Maia-Elkhoury AN, Reveiz L, Elias VM, Tweed JA Tags: Cochrane Database Syst Rev Source Type: research