Factors Affecting the Penetration of Niosome into the Skin, Their Laboratory Measurements and Dependency to the Niosome Composition: A Review.

Factors Affecting the Penetration of Niosome into the Skin, Their Laboratory Measurements and Dependency to the Niosome Composition: A Review. Curr Drug Deliv. 2020 Aug 20;: Authors: Khailnezhad B, Hadjizadeh A Abstract Skin, the most significant protective organ in the body, may face serious problems, including cancer, infectious diseases, etc., requiring different drugs for the treatment. However, most of these drugs have poor chemical and physical stability, and insufficient penetration through the skin layers. In recent years, with the development of nanotechnology, it has been possible to load a variety of drugs into nanocarriers, to effectively targeted drug delivery. The unique structure of niosome, presents an effective novel drug delivery system with the ability to load both hydrophilic and lipophilic drugs, having many potential therapeutic applications including skin treatment. However, surveying and discussing these recent, rapidly growing reported studies along with their theoretical principals is required for the full understanding and exploring the great potential of this approach in skin diseases and cosmetic treatments. To this aim, emphasis has been given to the factors affecting the penetration of niosome into the skin and their laboratory measurements and dependency to the niosome composition. In sum, longer tail surfactants for storing hydrophobic drugs and intracellular passing and surfactants with a large head ...
Source: Current Drug Delivery - Category: Drugs & Pharmacology Authors: Tags: Curr Drug Deliv Source Type: research