Improved Therapeutic Efficacy of Topotecan Against A549 Lung Cancer Cells with Folate-targeted Topotecan Liposomes.

CONCLUSION: The folate-targeted topotecan liposomes are effective drug delivery systems and can be easily modified with folate, enabling the targeted liposomes to deliver topotecan to lung cancer cells and kill them, which could be used as potential carriers for lung chemotherapy. PMID: 32851958 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32851958?dopt=Abstract

Source: Current Drug Metabolism - August 19, 2020 Category: Drugs & Pharmacology Authors: Zhang J, Shi W, Xue G, Ma Q, Cui H, Zhang L Tags: Curr Drug Metab Source Type: research