HDL (High-Density Lipoprotein) Remodeling and Magnetic Resonance Imaging-Assessed Atherosclerotic Plaque Burden: Study in a Preclinical Experimental Model.

CONCLUSIONS: HDL particles isolated from a hypercholesterolemic milieu lose their ability to regress and stabilize atherosclerotic lesions. Our data suggest that HDL remodeling in patients with co-morbidities may lead to the loss of HDL atheroprotective functions.
PMID: 32847390 [PubMed - as supplied by publisher]

Source: Arteriosclerosis, Thrombosis and Vascular Biology - August 26, 2020 Category: Cardiology Authors: Ben-Aicha S, Casaní L, Muñoz-García N, Joan-Babot O, Peña E, Aržanauskaitė M, Gutierrez M, Mendieta G, Padró T, Badimon L, Vilahur G Tags: Arterioscler Thromb Vasc Biol Source Type: research