Mendelian Randomization Analysis of Hemostatic Factors and Their Contribution to Peripheral Artery Disease.

CONCLUSIONS: Our results suggest a role for hemostasis, and by extension, thrombosis in PAD. Further study is warranted to determine whether VWF and FVIII independently affect the biology of PAD.
PMID: 32847391 [PubMed - as supplied by publisher]

Source: Arteriosclerosis, Thrombosis and Vascular Biology - August 26, 2020 Category: Cardiology Authors: Small AM, Huffman JE, Klarin D, Sabater-Lleal M, Lynch JA, Assimes TL, Sun YV, Miller D, Freiberg MS, Morrison AC, Rader DJ, Wilson PWF, Cho K, Tsao PS, Chang KM, Smith NL, O'Donnell CJ, de Vries PS, Damrauer SM, Cohorts for Heart and Aging Research in Ge Tags: Arterioscler Thromb Vasc Biol Source Type: research