Host tissue T cells may have an unexpected role in graft-versus-host disease

(Brigham and Women's Hospital) A new study has found that skin and intestinal T cells in the recipient survive conditioning regimens and continue to perform their normal functions. Under certain conditions, these T cells can become activated by donor white blood cells and play a previously unappreciated role in acute GVHD.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news