Why Airway Gland Secretions Are Abnormally Sticky in Cystic Fibrosis, and Why Not Much Can Be Done About It.

Why Airway Gland Secretions Are Abnormally Sticky in Cystic Fibrosis, and Why Not Much Can Be Done About It. Dev Cell. 2020 Aug 24;54(4):427-428 Authors: Widdicombe JH Abstract In this issue of Developmental Cell, Xie et al. show that in cystic fibrosis, airway gland mucus gels form under conditions of high acidity and protein concentration. This causes them to be unusually stiff. This abnormal rheology cannot be corrected by changing pH or calcium levels in the bathing medium. PMID: 32841592 [PubMed - in process]
Source: Developmental Cell - Category: Cytology Authors: Tags: Dev Cell Source Type: research