Prevalence of Plasmodium falciparum Kelch 13 (PfK13) and ubiquitin-specific protease 1 (pfubp1) gene polymorphisms in returning travellers from Africa reported in Eastern China.

This study showed limited variation in PfK13 among returning travellers from African countries and suggested other potential molecular markers, such as pfubp1, for use in surveillance of African isolates in ACT susceptibility studies. Further clinical trials research is under way to investigate these PfK13 and pfubp1 mutations, as well as other candidate molecular markers, and their roles in delaying parasite clearance. PMID: 32839222 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32839222?dopt=Abstract

Source: Antimicrobial Agents and Chemotherapy - August 23, 2020 Category: Microbiology Authors: Yan H, Kong X, Zhang T, Xiao H, Feng X, Tu H, Feng J Tags: Antimicrob Agents Chemother Source Type: research