Cortical Hyperostosis after Long-Lasting Prostaglandin E1 Treatment in a Newborn with Complex Congenital Heart Disease

A newborn girl was affected by a “ductal-dependent” complex congenital heart disease, which necessitated a long period of prostaglandin (prostaglandin E1) infusion; during this treatment, she developed cortical hyperostosis of the long bones. The patient was originally treated with antibiotics for a neonatal Staphylococcus aure us infection complicated with endocarditis and conjunctivitis. After 2 months of prostaglandin infusion, she presented with an antalgic position of the legs and was suspected to have a septic articular complication of the hip joints.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: Insights and Images Source Type: research