Posterior Reversible Encephalopathy Syndrome after Allogeneic Stem Cell Transplantation in Pediatric Patients with Fanconi Anemia, a Prospective Study

Posterior Reversible Encephalopathy Syndrome (PRES) encompasses a potential reversible neurologic syndrome with broad clinical manifestations; most commonly presented as seizure, headache, or altered mental status. The classic form is described on CT/MRI imaging as relatively symmetric transient cerebral vasogenic edema in the parieto-occipital cortex and subcortical white matter; however, various atypical forms with a wide spectrum of imaging features have been described [1,2]. Some atypical imaging patterns such as vasogenic edema in unusual regions, ischemic or hemorrhagic transformation, and irreversibility of findings in a substantial percentage of patients, provide a big challenge for diagnosis and management [3].

Source: Biology of Blood and Marrow Transplantation - August 25, 2020 Category: Hematology Authors: Maryam Behfar, Mohammad Babaei, Amir Reza Radmard, Soheil Kooraki, Hamid Farajifard, Parisa Naji, Sahar Taebi, Amir Ali Hamidieh Source Type: research