Longitudinal study of rpe65-associated inherited retinal degenerations

Conclusion: All patients with RPE65-associated IRDs developed symptoms within the first year of life. Visual function in childhood and adolescence varied but deteriorated inevitably toward blindness after age 40. In this study, genotype was not predictive of clinical course. The variance in severity of disease could not be explained by double hits in other IRD genes.
Source: RETINA - Category: Opthalmology Tags: Original Study Source Type: research