Targeted Informatics for Optimal Detection, Characterization, and Quantification of FLT3 Internal Tandem Duplications Across Multiple Next-Generation Sequencing Platforms

In this study, data from multiple NGS platforms —anchored multiplex PCR (AMP), amplicon [TruSeq Custom Amplicon (TSCA)], and hybrid-capture—were analyzed through a custom algorithm, including platform-specific measures of AR.

Source: Journal of Molecular Diagnostics - June 26, 2020 Category: Pathology Authors: Harrison K. Tsai, Diane G. Brackett, David Szeto, Ryan Frazier, Allison MacLeay, Phani Davineni, Danielle K. Manning, Elizabeth Garcia, Neal I. Lindeman, Long P. Le, Jochen K. Lennerz, Christopher J. Gibson, R. Coleman Lindsley, Annette S. Kim, Valentina Tags: Regular article Source Type: research