Effects of zinc porphyrin and zinc phthalocyanine derivatives in photodynamic anticancer therapy under different partial pressures of oxygen in vitro

In conclusion, our observations suggest that PDT can be effective even in hypoxic conditions if a suitable sensitizer is chosen, such as ZnPcS2, which can inhibit mitochondrial respiration.

http://link.springer.com/10.1007/s10637-020-00990-7

Source: Investigational New Drugs - August 23, 2020 Category: Drugs & Pharmacology Source Type: research