Core Outcome Set Development for Adolescent Major Depressive Disorder Clinical Trials: A Registered Report
Major Depressive Disorder (MDD), associated with life-time prevalence rates of 11% in adolescents, results in significant disease burden worldwide.1 Adolescent MDD clinical trials evaluate interventions by measuring the effects of the interventions on various treatment outcomes, such as “severity of depressive symptoms” or “social functioning”.2 The ability to compare or contrast treatments and generate usable, meaningful data however, depends on trials using well-selected and well-defined outcomes measured by validated tools.
Source: Journal of the American Academy of Child and Adolescent Psychiatry - Category: Psychiatry Authors: Suneeta Monga, Andrea Monsour, Emma Stallwood, Riddhi Desai, Kristin Cleverley, Darren Courtney, Joanna Henderson, Daphne Korczak, Karolin Krause, Maureen Smith, Peter Szatmari, Martin Offringa, Nancy Butcher Tags: Study Preregistration Source Type: research
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