Efficient Definitive Endoderm Differentiation from Human Parthenogenetic Embryonic Stem Cells Induced by Activin A and Wnt3a.

CONCLUSIONS: Through the combination treatment using activin A and Wnt3a, DE differentiation from hPESCs culminated at 48 h, which can be regarded as the optimal time-point to induce differentiation of endodermal cells such as pancreatic, liver, and intestinal cells.
PMID: 32826243 [PubMed - as supplied by publisher]

Source: Annals of Clinical and Laboratory Science - June 30, 2020 Category: Laboratory Medicine Authors: Liang R, Xiao X, Luo L, Chen T, Yang H, Wang W, Zhang Y, Wang Z Tags: Ann Clin Lab Sci Source Type: research