Involvement of peroxisome proliferator-activated receptors in cardiac and vascular remodeling in a novel minipig model of insulin resistance and atherosclerosis induced by consumption of a high-fat/cholesterol diet

Conclusions:
These data suggest that HFC-fed Tibetan minipigs develop IR and AS and that PPARs are involved in cardiovascular remodeling and impaired function.

Source: Cardiovascular Diabetology - January 16, 2015 Category: Cardiology Authors: Pan YongmingCai ZhaoweiMa YichaoZhu KeyanChen LiangChen FangmingXu XiaopingMa QuanxinChen Minli Source Type: research